Research
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Classification of Multivariate Functional Data with an Application to ADHD fMRI Data
Seong, Y., Gauran, I. I., Kim, H., Ombao, H., & Park, J. Journal of Applied Statistics, 53(8), 1515–1537 (2026).
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Analysis of Experiments with High Frequency Time Series Responses and the Implications for Power and Sample Size
Rafor, B., Gauran, I., Ombao, H., Lansangan, J. R., & Barrios, E. Scientific Reports, 15(1), 1–25 (2025).
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Causal Relationships Between Diseases Mined from the Literature Improve the Use of Polygenic Risk Scores
Toonsi, S., Gauran, I., Ombao, H., Schofield, P. N., & Hoehndorf, R. Bioinformatics, 40(11), btae639 (2024).
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Bayesian Local False Discovery Rate for Sparse Count Data with Application to the Discovery of Hotspots in Protein Domains
Gauran, I., Park, J., Rattsev, I., Peterson, T., Kann, M., & Park, D. The Annals of Applied Statistics, 16(3), 1459–1475 (2022).
Projects
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GapYears: Replicating the Healthspan-Lifespan Gap
A published finding, rebuilt from public WHO data instead of trusted on the page, with the parts that would not reproduce cleanly left visible rather than smoothed over.
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BloodVsMethylation: Two PhenoAges, Two Answers
Two measures of biological age, trained toward the same target, disagree about race in the same people. A replication in public data, and an attempt to take the disagreement apart.
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NeighborsMailer: The Postcard, Matched to the Digit
A famous field experiment rebuilt in Python from the authors' raw data, checked against their own Stata log to the last printed digit, then turned into the yes-or-no a campaign actually needs.
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AncovaThreeWays: One FDA Table, Proved
The primary result of a public Alzheimer's trial submission, rebuilt from raw data in Python and in R, proved value by value in Lean, then refitted the way a trial would handle dropouts today.
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PlaceboVsObserved: Two Designs, One Vaccine
The 1954 Salk polio trial ran a randomized design and a cheaper observed one side by side. A rebuild of the 1955 report's arithmetic in Python and R, and the 9-point gap between the designs taken apart.
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ColonAdjuvant: The Approval, Rechecked
The trial behind the 1990 approval of levamisole plus 5-FU for colon cancer, rebuilt from raw data in Python and in R, the verdict proved in exact arithmetic, and the mismatches with the paper left in view.
Essays
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Put a Pin on It
A pharmacy still gives its address from a fig tree that fell in 1991: what directions count from, and how a pin leads back once the landmark is gone.
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The Dash Between the Dates
I reran the WHO's numbers for 185 countries: the gap between living long and living well grew for two decades, then closed from the wrong end. Why both ends of a gap get written down first.
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What the Fix Cost
Twenty-three cats parachuted into Borneo to repair a malaria fix, and what systems thinking asks before the next one: where the cost will show up, and when.
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Twelve Questions, Invited in for Tea
The twelve questions I keep for life, seated like guests at a tea table: how a question earns a chair, and where each one sits.
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Gifts to a Future Self
Ulam's solitaire tally and a ladder of whys: how counting a habit shows who I am becoming, one small gift at a time.
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Significant but Wrong
A nurse's bad feeling went into a spreadsheet and came out 1 in 342 million: what that count assumed, and what a significant result cannot say. My own field, hypothesis testing.